Pulmonary and Critical Care

Allergies, also referred to as allergic diseases, are variety of conditions caused by hypersensitivity of the system to typically harmless substances within the environment.These diseases include pollinosis , food allergies, atopic eczema , allergic asthma, and anaphylaxis.

Common allergens include pollen and certain foods. Metals and other substances can also cause such problems. Food, insect stings, and medications are common causes of severe reactions. Their development is thanks to both genetic and environmental factors. The underlying mechanism involves immunoglobulin E antibodies (IgE), a part of the body's system , binding to an allergen then to a receptor on mast cells or basophils where it triggers the discharge of inflammatory chemicals like histamine.